Welcome to the Landau Lab for Structural Biology and Small-molecule Design
Lab’s Date of Birth: September 2012
Revealing the molecular and atomic details of protein function and regulation is imperative when trying to develop drugs that will accurately intervene with cellular processes. Our lab focuses on the mechanistic details of regulation in proteins that are central to physiological and pathophysiological processes. The main project in the lab is investigating novel targets for antimicrobial drugs against key virulence determinants such as biofilms. This direction was motivated by the frightening rapid increase in the occurrence of antibiotic resistance to many common bacterial pathogens, in addition to the drastic reduction in the approval of new antibacterial drugs.
We are grateful for funding from the Technion, DIP – Deutsch-Israelische Projektkooperation, University of Michigan – Israel Collaborative Research Grant, U.S.-Israel Binational Science Foundation (BSF), Marie Curie Reintegration Grant, the I-CORE Program of the Planning and Budgeting Committee and The Israel Science Foundation (I-CORE Center of Excellence in Integrated Structural Cell Biology), Umbrella Cooperation – When Life Sciences and Engineering Converge, Eliyahu Pen research Fund, Mallat Family Research Fund, J. and A. Taub Biological Research, and Alon Fellowship from the Israeli Council for Higher Education.